Renal Complications Associated with HIV IAIDS Infections in Donka National Hospital, Conakry, Guinee

Abstract

This is a crossectional study, undertaken from August 1st 2003 to July 31st 2004 on patients hospitalized at Donka National Hospital (Conakry). The purpose was to determine the frequency of renal complications associated with infections by the human immunodeficiency virus (HIV/AIDS). We included patients who were investigated for renal disease. Forty five out of 108 patients (41.7%) demonstrated renal complications. The sex ratio (M/F) was 1.04 (24 men/21 women). The mean age was 40.4 ± 9.6 years (range 20-58 years). The age groups most affected were those between 25 and 49 years (75.55%). Monogamous patients held the first rank (51.11 %), followed by polygamous patients (28.89%) and bachelors (20%). Serology was positive for HIV 1 in 42 patients (93.33%) and for HIV-2 in 3 patients (6.67%); there were no cases of co-infection with HIV-l and 2. Renal complications consisted of acute renal failure: 24 cases (53.33%), chronic renal failure: 13 cases (28.89%), nephrotic syndrome: 4 cases:
(8.89%) and interstitial nephritis: 4 cases (8.89%). We concluded that renal complications are common in HIV patients in Guinea and recommend early screening and treatment of these complications.